Alpha-Blockers Treatment For Benign Prostatic Hypertrophy (BPH) header graphic

Alpha-Blockers Treatment For Benign Prostatic Hypertrophy (BPH)

Terazosin (Blavin): Approved in 1993.

  • Life 1 / 2 12hrs. Should be given 1mg x 3 then 2mg x12 and then 5mg/day.
  • 40% is eliminated by the kidney and 60% in feces.
  • Deterioration of renal function does not change the dose.
  • Produces decreased total and LDL cholesterol <5%.
  • Lower BP in hypertension but with minimal effect in normotensives.
  • 70% improvement in symptoms: 60% obstructive, 30% and 35% flow irritant.
  • RAM: dizziness 9%, fatigue 7%, orthostatic 4%, drowsiness 3%.

Doxazosin (Cardura): Approved in 1995.

  • Life 1 / 2 22hrs. Should be given 1 mg for 1 to 2 weeks and then 2mg.
  • Very similar to the previous in terms of renal function and lipid profile.
  • 70% improvement in symptoms.
  • RAM: syncope 15% (give it at night when lying down), rest well.

Tamsulosin (Secotex): Approved in 1997.

  • Dosage 0.4 to 0.8 mg / day. 1st is an alpha blocker, 12 times more selective.
  • Rapid decrease in symptoms after the first shot.
  • Significant increase in urinary flow 5hrs after the first dose.
  • RAM: abnormal ejaculation 5%.

Inhibitors of 5 alpha reductase

  • Finasteride (Proscar). Adopted in 1992.
  • Life 1 / 2 8hrs. Increased utility in prostates> 40grs.
  • PSA decreases by 50%, so after 6 months of PSA obtained el.valor multiply by two.
  • Minimal effects on sex drive.
  • Does not meet the dose in renal failure.
  • RAM: 4% impotence libido decreased 3%.

Prostate Cancer










Gleason Score

Prostate Specific Antigen

Useful Resources

Prostate Cancer

Other Prostate Problems

Prostate Infection

Prostate Infection Symptoms

Surgical Treatment of BPH

Symptoms of BPH

Prostatitis Symptoms

Treatment of prostatitis

Symptoms of Prostate Problems

Symptoms and Diagnosis of Prostatitis

Alpha-Blockers Treatment For Benign Prostatic Hypertrophy

Benign Prostatic Hypertrophy

Causes, Prevention & Treatment Of Prostate Problems

Natural Treatments Of Prostatitis

Prostatitis A chronic Prostate Problem

Prostate Adenoma

Major Prostate Problems

Privacy Policy